Ontology highlight
ABSTRACT:
SUBMITTER: Broeckx BJG
PROVIDER: S-EPMC5688105 | biostudies-literature | 2017 Nov
REPOSITORIES: biostudies-literature
Broeckx Bart J G BJG Derrien Thomas T Mottier Stéphanie S Wucher Valentin V Cadieu Edouard E Hédan Benoît B Le Béguec Céline C Botherel Nadine N Lindblad-Toh Kerstin K Saunders Jimmy H JH Deforce Dieter D André Catherine C Peelman Luc L Hitte Christophe C
Scientific reports 20171115 1
Genome-wide association studies (GWAS) are widely used to identify loci associated with phenotypic traits in the domestic dog that has emerged as a model for Mendelian and complex traits. However, a disadvantage of GWAS is that it always requires subsequent fine-mapping or sequencing to pinpoint causal mutations. Here, we performed whole exome sequencing (WES) and canine high-density (cHD) SNP genotyping of 28 dogs from 3 breeds to compare the SNP and linkage disequilibrium characteristics toget ...[more]