Ontology highlight
ABSTRACT:
SUBMITTER: Kozak RA
PROVIDER: S-EPMC5691648 | biostudies-literature | 2017 Oct
REPOSITORIES: biostudies-literature
Kozak Robert A RA Majer Anna A Biondi Mia J MJ Medina Sarah J SJ Goneau Lee W LW Sajesh Babu V BV Slota Jessy A JA Zubach Vanessa V Severini Alberto A Safronetz David D Hiebert Shannon L SL Beniac Daniel R DR Booth Timothy F TF Booth Stephanie A SA Kobinger Gary P GP
Viruses 20171014 10
The Zika virus (ZIKV) epidemic is an ongoing public health concern. ZIKV is a flavivirus reported to be associated with microcephaly, and recent work in animal models demonstrates the ability of the virus to cross the placenta and affect fetal brain development. Recent findings suggest that the virus preferentially infects neural stem cells and thereby deregulates gene expression, cell cycle progression, and increases cell death. However, neuronal stem cells are not the only brain cells that are ...[more]