Ontology highlight
ABSTRACT:
SUBMITTER: Girolomoni G
PROVIDER: S-EPMC5697699 | biostudies-literature | 2017 Oct
REPOSITORIES: biostudies-literature
Girolomoni G G Strohal R R Puig L L Bachelez H H Barker J J Boehncke W H WH Prinz J C JC
Journal of the European Academy of Dermatology and Venereology : JEADV 20170829 10
Psoriasis is a chronic, immune-mediated disease affecting more than 100 million people worldwide and up to 2.2% of the UK population. The aetiology of psoriasis is thought to originate from an interplay of genetic, environmental, infectious and lifestyle factors. The manner in which genetic and environmental factors interact to contribute to the molecular disease mechanisms has remained elusive. However, the interleukin 23 (IL-23)/T-helper 17 (T<sub>H</sub> 17) immune axis has been identified as ...[more]