Ontology highlight
ABSTRACT:
SUBMITTER: Howard J
PROVIDER: S-EPMC5698852 | biostudies-literature | 2017 Nov
REPOSITORIES: biostudies-literature
Howard Jonathon J Garzon-Coral Carlos C
BioEssays : news and reviews in molecular, cellular and developmental biology 20170928 11
Tissues are shaped and patterned by mechanical and chemical processes. A key mechanical process is the positioning of the mitotic spindle, which determines the size and location of the daughter cells within the tissue. Recent force and position-fluctuation measurements indicate that pushing forces, mediated by the polymerization of astral microtubules against- the cell cortex, maintain the mitotic spindle at the cell center in Caenorhabditis elegans embryos. The magnitude of the centering forces ...[more]