Ontology highlight
ABSTRACT:
SUBMITTER: Chen L
PROVIDER: S-EPMC5699061 | biostudies-literature | 2017 Nov
REPOSITORIES: biostudies-literature
Chen Lihe L Lee Jae Wook JW Chou Chung-Lin CL Nair Anil V AV Battistone Maria A MA Păunescu Teodor G TG Merkulova Maria M Breton Sylvie S Verlander Jill W JW Wall Susan M SM Brown Dennis D Burg Maurice B MB Knepper Mark A MA
Proceedings of the National Academy of Sciences of the United States of America 20171031 46
Prior RNA sequencing (RNA-seq) studies have identified complete transcriptomes for most renal epithelial cell types. The exceptions are the cell types that make up the renal collecting duct, namely intercalated cells (ICs) and principal cells (PCs), which account for only a small fraction of the kidney mass, but play critical physiological roles in the regulation of blood pressure, extracellular fluid volume, and extracellular fluid composition. To enrich these cell types, we used FACS that empl ...[more]