Ontology highlight
ABSTRACT:
SUBMITTER: Menck K
PROVIDER: S-EPMC5699186 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Journal of extracellular vesicles 20170926 1
Extracellular vesicles (EVs) are membrane particles secreted from cells into all body fluids. Several EV populations exist differing in size and cellular origin. Using differential centrifugation EVs pelleting at 14,000 g ("microvesicles" (MV)) and 100,000 g ("exosomes") are distinguishable by protein markers. Neutral sphingomyelinase (nSMase) inhibition has been shown to inhibit exosome release from cells and has since been used to study their functional implications. How nSMases (also known as ...[more]