Ontology highlight
ABSTRACT:
SUBMITTER: McCulley CH
PROVIDER: S-EPMC5699452 | biostudies-literature | 2017 Aug
REPOSITORIES: biostudies-literature
Journal of the American Chemical Society 20170803 32
Results of kinetic experiments and quantum chemical computations on a series of platinum-promoted polycyclization reactions are described. Analyses of these results reveal a reactivity model that reaches beyond the energetics of the cascade itself, incorporating an ensemble of pre-cyclization conformations of the platinum-alkene reactant complex, only a subset of which are productive for bi- (or larger) cyclization and lead to products. Similarities and differences between this scenario, includi ...[more]