Assortative Mating by Ethnicity in Longevous Families.
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ABSTRACT:
SUBMITTER: Sebastiani P
PROVIDER: S-EPMC5702482 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Publications
Assortative Mating by Ethnicity in Longevous Families.
Sebastiani Paola P Gurinovich Anastasia A Bae Harold H Andersen Stacy L SL Perls Thomas T TT
Frontiers in genetics 20171121
Recent work shows strong evidence of ancestry-based assortative mating in spouse pairs of the older generation of the Framingham Heart Study. Here, we extend this analysis to two studies of human longevity: the Long Life Family Study (LLFS), and the New England Centenarian Study (NECS). In the LLFS, we identified 890 spouse pairs spanning two generations, while in the NECS we used data from 102 spouse pairs including offspring of centenarians. We used principal components of genome-wide genotype ...[more]
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