Ontology highlight
ABSTRACT:
SUBMITTER: Weisser H
PROVIDER: S-EPMC5703597 | biostudies-literature | 2016 Dec
REPOSITORIES: biostudies-literature
Weisser Hendrik H Wright James C JC Mudge Jonathan M JM Gutenbrunner Petra P Choudhary Jyoti S JS
Journal of proteome research 20161110 12
Proteogenomics leverages information derived from proteomic data to improve genome annotations. Of particular interest are "novel" peptides that provide direct evidence of protein expression for genomic regions not previously annotated as protein-coding. We present a modular, automated data analysis pipeline aimed at detecting such "novel" peptides in proteomic data sets. This pipeline implements criteria developed by proteomics and genome annotation experts for high-stringency peptide identific ...[more]