Ontology highlight
ABSTRACT:
SUBMITTER: Mehla J
PROVIDER: S-EPMC5705681 | biostudies-literature | 2017 Nov
REPOSITORIES: biostudies-literature
Mehla Jitender J Dedrick Rebekah M RM Caufield J Harry JH Wagemans Jeroen J Sakhawalkar Neha N Johnson Allison A Hatfull Graham F GF Uetz Peter P
Scientific reports 20171128 1
Mycobacteriophage are viruses that infect mycobacteria. More than 1,400 mycobacteriophage genomes have been sequenced, coding for over one hundred thousand proteins of unknown functions. Here we investigate mycobacteriophage Giles-host protein-protein interactions (PPIs) using yeast two-hybrid screening (Y2H). A total of 25 reproducible PPIs were found for a selected set of 10 Giles proteins, including a putative virion assembly protein (gp17), the phage integrase (gp29), the endolysin (gp31), t ...[more]