Ontology highlight
ABSTRACT:
SUBMITTER: Li W
PROVIDER: S-EPMC5706003 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Li Weiyang W Qi Yanwei Y Cui Xiaofang X Sun Yuhui Y Huo Qing Q Yang Yan Y Wen Xinyuan X Tan Meihua M Du Shiyi S Zhang Huali H Zhang Meng M Liu Chuanxin C Kong Qingsheng Q
Journal of Cancer 20171023 19
Hepatocellular carcinoma (HCC) is the third leading cause of cancer mortality worldwide. In this study, we had analysed the copy number variations and heteroplasmic mutations of mitochondria (MT) in 88 HCC individuals. The average copy number of MT genome in normal samples was significantly greater than that in tumor samples. Overall, the number of heteroplasmic mutations in 88 tumor and their matched normal samples were 241 and 173, respectively. There was higher positive ratio of heteroplasmic ...[more]