Ontology highlight
ABSTRACT:
SUBMITTER: Hyde CL
PROVIDER: S-EPMC5706769 | biostudies-literature | 2016 Sep
REPOSITORIES: biostudies-literature
Hyde Craig L CL Nagle Michael W MW Tian Chao C Chen Xing X Paciga Sara A SA Wendland Jens R JR Tung Joyce Y JY Hinds David A DA Perlis Roy H RH Winslow Ashley R AR
Nature genetics 20160801 9
Despite strong evidence supporting the heritability of major depressive disorder (MDD), previous genome-wide studies were unable to identify risk loci among individuals of European descent. We used self-report data from 75,607 individuals reporting clinical diagnosis of depression and 231,747 individuals reporting no history of depression through 23andMe and carried out meta-analysis of these results with published MDD genome-wide association study results. We identified five independent variant ...[more]