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Low-Energy Collisions of Protonated Enantiopure Amino Acids with Chiral Target Gases.

ABSTRACT: Here we report on the gas-phase interactions between protonated enantiopure amino acids (L- and D-enantiomers of Met, Phe, and Trp) and chiral target gases [(R)- and (S)-2-butanol, and (S)-1-phenylethanol] in 0.1-10.0 eV low-energy collisions. Two major processes are seen to occur over this collision energy regime, collision-induced dissociation and ion-molecule complex formation. Both processes were found to be independent of the stereo-chemical composition of the interacting ions and targets. These data shed light on the currently debated mechanisms of gas-phase chiral selectivity by demonstrating the inapplicability of the three-point model to these interactions, at least under single collision conditions. Graphical Abstract.

SUBMITTER: Kulyk K

PROVIDER: S-EPMC5707228 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature

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Low-Energy Collisions of Protonated Enantiopure Amino Acids with Chiral Target Gases.

Kulyk K K Rebrov O O Ryding M M Thomas R D RD Uggerud E E Larsson M M

Journal of the American Society for Mass Spectrometry 20170921 12

Here we report on the gas-phase interactions between protonated enantiopure amino acids (L- and D-enantiomers of Met, Phe, and Trp) and chiral target gases [(R)- and (S)-2-butanol, and (S)-1-phenylethanol] in 0.1-10.0 eV low-energy collisions. Two major processes are seen to occur over this collision energy regime, collision-induced dissociation and ion-molecule complex formation. Both processes were found to be independent of the stereo-chemical composition of the interacting ions and targets. ...[more]

PMID: 28936701

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