Ontology highlight
ABSTRACT:
SUBMITTER: Bacigalupo A
PROVIDER: S-EPMC5709112 | biostudies-literature | 2017 Dec
REPOSITORIES: biostudies-literature
Haematologica 20170929 12
Patients with acute graft-<i>versus</i>-host disease (GvHD) grade I were randomized to an observation arm (n=85) or to a treatment arm (n=86) consisting of 6-methylprednisolone 1 mg/kg/day, after stratification for age and donor type. The primary end point was development of grade II-IV GvHD. The cumulative incidence of grade II-IV GvHD was 50% in the observation arm and 33% in the treatment arm (<i>P</i>=0.005). However, grade III-IV GvHD was comparable (13% <i>vs</i> 10%, respectively; <i>P</i ...[more]