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Restoration of anatomical continuity after spinal cord transection depends on Wnt/?-catenin signaling in larval zebrafish.

ABSTRACT: This data article contains descriptive and experimental data on spinal cord regeneration in larval zebrafish and its dependence on Wnt/?-catenin signaling. Analyzing spread of intraspinally injected fluorescent dextran showed that anatomical continuity is rapidly restored after complete spinal cord transection. Pharmacological interference with Wnt/?-catenin signaling (IWR-1) impaired restoration of spinal continuity. For further details and experimental findings please refer to the research article by Wehner et al. Wnt signaling controls pro-regenerative Collagen XII in functional spinal cord regeneration in zebrafish (Wehner et al., 2017) [1].

SUBMITTER: Wehner D

PROVIDER: S-EPMC5709348 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature

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Restoration of anatomical continuity after spinal cord transection depends on Wnt/β-catenin signaling in larval zebrafish.

Wehner Daniel D Becker Thomas T Becker Catherina G CG

Data in brief 20171104

This data article contains descriptive and experimental data on spinal cord regeneration in larval zebrafish and its dependence on Wnt/β-catenin signaling. Analyzing spread of intraspinally injected fluorescent dextran showed that anatomical continuity is rapidly restored after complete spinal cord transection. Pharmacological interference with Wnt/β-catenin signaling (IWR-1) impaired restoration of spinal continuity. For further details and experimental findings please refer to the research art ...[more]

PMID: 29204466

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