Ontology highlight
ABSTRACT:
SUBMITTER: Aman AJ
PROVIDER: S-EPMC6072442 | biostudies-literature | 2018 Jul
REPOSITORIES: biostudies-literature
Aman Andrew J AJ Fulbright Alexis N AN Parichy David M DM
eLife 20180717
Understanding how patterning influences cell behaviors to generate three dimensional morphologies is a central goal of developmental biology. Additionally, comparing these regulatory mechanisms among morphologically diverse tissues allows for rigorous testing of evolutionary hypotheses. Zebrafish skin is endowed with a coat of precisely patterned bony scales. We use <i>in-toto</i> live imaging during scale development and manipulations of cell signaling activity to elucidate core features of sca ...[more]