False-negative synovial alpha-defensin.
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ABSTRACT:
SUBMITTER: Adams JR
PROVIDER: S-EPMC5712026 | biostudies-literature | 2017 Dec
REPOSITORIES: biostudies-literature
Publications
False-negative synovial alpha-defensin.
Adams Jake R JR Schwartz Adam J AJ
Arthroplasty today 20170723 4
We present a case of chronic periprosthetic hip infection diagnosed using the Musculoskeletal Infection Society criteria as the gold standard. The alpha-defensin test was falsely negative. The diagnostic workup of the patient is detailed, along with a discussion regarding the potential reasons behind the misleading alpha-defensin results. To our knowledge, this is the first reported case of a false-negative alpha-defensin test in the setting of an open sinus tract communicating with a culture-po ...[more]
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