Ontology highlight
ABSTRACT:
SUBMITTER: de Candia P
PROVIDER: S-EPMC5714331 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
de Candia Paola P Spinetti Gaia G Specchia Claudia C Sangalli Elena E La Sala Lucia L Uccellatore Annachiara A Lupini Silvia S Genovese Stefano S Matarese Giuseppe G Ceriello Antonio A
PloS one 20171204 12
A major unmet medical need to better manage Type 2 Diabetes (T2D) is the accurate disease prediction in subjects who show glucose dysmetabolism, but are not yet diagnosed as diabetic. We investigated the possibility to predict/monitor the progression to T2D in these subjects by retrospectively quantifying blood circulating microRNAs in plasma of subjects with i) normal glucose tolerance (NGT, n = 9); ii) impaired glucose tolerance (IGT, n = 9), divided into non-progressors (NP, n = 5) and progre ...[more]