Ontology highlight
ABSTRACT:
SUBMITTER: Manohar A
PROVIDER: S-EPMC5714501 | biostudies-literature | 2017 Dec
REPOSITORIES: biostudies-literature
Manohar Anitha A Curtis Andre L AL Zderic Stephen A SA Valentino Rita J RJ
eLife 20171204
Urodynamic status must interact with arousal and attentional processes so that voiding occurs under appropriate conditions. To elucidate the central encoding of this visceral demand, multisite recordings were made within a putative pontine-cortical micturition circuit from the pontine micturition center (PMC), locus coeruleus (LC) and medial prefrontal cortex (mPFC) during cystometry in unanesthetized rats. PMC neurons had homogeneous firing patterns, characterized by tonic activity and phasic b ...[more]