Ontology highlight
ABSTRACT:
SUBMITTER: Alonso MF
PROVIDER: S-EPMC5715939 | biostudies-literature | 2017 Jun
REPOSITORIES: biostudies-literature
Alonso Maria F MF Gow Neil A R NAR Erwig Lars P LP Bain Judith M JM
Journal of fungi (Basel, Switzerland) 20170622 3
<i>Candida albicans</i> is an opportunistic fungal pathogen that infects immunocompromised patients. Infection control requires phagocytosis by innate immune cells, including macrophages. Migration towards, and subsequent recognition of, <i>C. albicans</i> fungal cell wall components by macrophages is critical for phagocytosis. Using live-cell imaging of phagocytosis, the macrophage cell line J774.1 showed enhanced movement in response to <i>C. albicans</i> cell wall mutants, particularly during ...[more]