Ontology highlight
ABSTRACT:
SUBMITTER: Tan Z
PROVIDER: S-EPMC5718353 | biostudies-literature | 2017 Feb
REPOSITORIES: biostudies-literature
Tan Zhijing Z Nie Song S McDermott Sean P SP Wicha Max S MS Lubman David M DM
Journal of proteome research 20170120 2
Cancers are initiated and developed from a small population of stem-like cells termed cancer stem cells (CSCs). There is heterogeneity among this CSC population that leads to multiple subpopulations with their own distinct biological features and protein expression. The protein expression and function may be impacted by amino acid variants that can occur largely due to single nucleotide changes. We have thus performed proteomic analysis of breast CSC subpopulations by mass spectrometry to study ...[more]