Mutations in RNA methylating enzymes in disease.
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ABSTRACT:
SUBMITTER: Stojkovic V
PROVIDER: S-EPMC5723530 | biostudies-literature | 2017 Dec
REPOSITORIES: biostudies-literature
Publications
Mutations in RNA methylating enzymes in disease.
Stojković Vanja V Fujimori Danica Galonić DG
Current opinion in chemical biology 20171020
RNA methylation is an abundant modification identified in various RNA species in both prokaryotic and eukaryotic organisms. However, the functional roles for the majority of these methylations remain largely unclear. In eukaryotes, many RNA methylations have been suggested to participate in fundamental cellular processes. Mutations in eukaryotic RNA methylating enzymes, and a consequent change in methylation, can lead to the development of diseases and disorders. In contrast, loss of RNA methyla ...[more]
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