Ontology highlight
ABSTRACT:
SUBMITTER: Pritchard JE
PROVIDER: S-EPMC5724196 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Pritchard Jayne-Louise E JE O'Mara Tracy A TA Glubb Dylan M DM
Frontiers in pharmacology 20171206
The development of new drugs has become challenging as the necessary investments in time and money have increased while drug approval rates have decreased. A potential solution to this problem is drug repositioning which aims to use existing drugs to treat conditions for which they were not originally intended. One approach that may enhance the likelihood of success is to reposition drugs against a target that has a genetic basis. The multitude of genome-wide association studies (GWASs) conducte ...[more]