Ontology highlight
ABSTRACT:
SUBMITTER: Bizzotto S
PROVIDER: S-EPMC5725533 | biostudies-literature | 2017 Dec
REPOSITORIES: biostudies-literature
Bizzotto Sara S Uzquiano Ana A Dingli Florent F Ershov Dmitry D Houllier Anne A Arras Guillaume G Richards Mark M Loew Damarys D Minc Nicolas N Croquelois Alexandre A Houdusse Anne A Francis Fiona F
Scientific reports 20171211 1
The ventricular zone (VZ) of the developing cerebral cortex is a pseudostratified epithelium that contains progenitors undergoing precisely regulated divisions at its most apical side, the ventricular lining (VL). Mitotic perturbations can contribute to pathological mechanisms leading to cortical malformations. The HeCo mutant mouse exhibits subcortical band heterotopia (SBH), likely to be initiated by progenitor delamination from the VZ early during corticogenesis. The causes for this are howev ...[more]