Ontology highlight
ABSTRACT:
SUBMITTER: Cao X
PROVIDER: S-EPMC5726787 | biostudies-literature | 2017 Nov
REPOSITORIES: biostudies-literature
Cell reports 20171101 6
Increasing evidence implies an extensive and universal interaction between the immune system and the nervous system. Previous studies showed that OCTR-1, a neuronal G-protein-coupled receptor (GPCR) analogous to human norepinephrine receptors, functions in sensory neurons to control the gene expression of both microbial killing pathways and the unfolded protein response (UPR) in Caenorhabditis elegans. Here, we found that OCTR-1-expressing neurons, ASH, are involved in controlling innate immune ...[more]