Ontology highlight
ABSTRACT:
SUBMITTER: Komiya M
PROVIDER: S-EPMC5727073 | biostudies-literature | 2017 Dec
REPOSITORIES: biostudies-literature
Komiya Maki M Ito Akihiro A Endo Mizuki M Hiruma Daisuke D Hattori Mitsuru M Saitoh Hisato H Yoshida Minoru M Ozawa Takeaki T
Scientific reports 20171212 1
Post-translational modification by the Small Ubiquitin-related Modifier (SUMO) is indispensable for diverse biological mechanisms. Although various attempts have been made to discover novel SUMO substrate proteins to unveil the roles of SUMOylation, the reversibility of SUMOylation, and the differences in the SUMOylation level still makes it difficult to explore infrequently-SUMOylated proteins in mammalian cells. Here, we developed a method to screen for mammalian SUMOylated proteins using the ...[more]