Ontology highlight
ABSTRACT:
SUBMITTER: Fan T
PROVIDER: S-EPMC5727777 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Fan Tao T Meng Wei-Dong WD Zhang Xingang X
Beilstein journal of organic chemistry 20171206
An efficient palladium-catalyzed Heck-type reaction of secondary trifluoromethylated alkyl bromides has been developed. The reaction proceeds under mild reaction conditions with high efficiency and excellent functional group tolerance, even towards formyl and hydroxy groups. Preliminary mechanistic studies reveal that a secondary trifluoromethylated alkyl radical is involved in the reaction. ...[more]