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Perioperative analgesia after intrathecal fentanyl and morphine or morphine alone for cesarean section: A randomized controlled study.


ABSTRACT: OBJECTIVES:Intrathecal morphine is used in the postoperative management of pain after caesarean section (CS), but might not be optimal for intraoperative analgesia. We hypothesized that intrathecal fentanyl could supplement intraoperative analgesia when added to a local anesthetic and morphine without affecting management of postoperative pain. METHODS:This prospective, randomized, double-blind, parallel-group study included 60 parturients scheduled for elective CS. Spinal anesthesia consisted of bupivacaine with either morphine 100??g (M group), or fentanyl 25??g and morphine 100??g (FM group). The frequency of intraoperative pain and pethidine consumption in the 24?hours postoperatively was recorded. RESULTS:Fewer patients in the FM group required additional intraoperative analgesia (P?

SUBMITTER: Weigl W 

PROVIDER: S-EPMC5728777 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature

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Perioperative analgesia after intrathecal fentanyl and morphine or morphine alone for cesarean section: A randomized controlled study.

Weigl Wojciech W   Bieryło Andrzej A   Wielgus Monika M   Krzemień-Wiczyńska Świetlana Ś   Kołacz Marcin M   Dąbrowski Michał J MJ  

Medicine 20171201 48


<h4>Objectives</h4>Intrathecal morphine is used in the postoperative management of pain after caesarean section (CS), but might not be optimal for intraoperative analgesia. We hypothesized that intrathecal fentanyl could supplement intraoperative analgesia when added to a local anesthetic and morphine without affecting management of postoperative pain.<h4>Methods</h4>This prospective, randomized, double-blind, parallel-group study included 60 parturients scheduled for elective CS. Spinal anesthe  ...[more]

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