Crystal structures of two (Z)-2-(4-oxo-1,3-thia-zolidin-2-yl-idene)acetamides.

ABSTRACT: The crystal structures of two (oxo-thia-zolidin-2-yl-idene)acetamides, namely (Z)-2-[2-(morpholin-4-yl)-2-oxo-ethyl-idene]thia-zolidin-4-one, C₉H₁₂N₂O₃S, (I), and (Z)-N-(4-meth-oxy-phen-yl)-2-(4-oxo-thia-zolidin-2-yl-idene)acetamide, C₁₂H₁₂N₂O₃S, (II), are described and compared with a related structure. The Z conformation was observed for both the compounds. In (I), the morpholin-4-yl ring has a chair conformation and its mean plane is inclined to the thia-zolidine ring mean plane by 37.12?(12)°. In (II), the benzene ring is inclined to the mean plane of the thia-zolidine ring by 20.34?(14)°. In the crystal of (I), mol-ecules are linked by N-H?O hydrogen bonds, forming C(6) chains along the b-axis direction. The edge-to-edge arrangement of the mol-ecules results in short C-H?O and C-H?S inter-actions, which consolidate the chain into a ribbon-like structure. In the crystal of (II), two N-H?O hydrogen bonds result in the formation of C(8) chains along the b-axis direction and C(6) chains along the c-axis direction. The combination of these inter-actions leads to the formation of layers parallel to the bc plane, enclosing R₄⁴(28) rings involving four mol-ecules.

SUBMITTER: Galushchinskiy A 

PROVIDER: S-EPMC5730238 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature