Crystal structures of 1-benzene-sulfon-yl-2-methyl-3-(4-nitro-benzoyl)-2,3-di-hydro-1H-indole and 1-benzene-sulfon-yl-2-methyl-3-[(thio-phen-2-yl)carbon-yl]-2,3-di-hydro-1H-indole.

ABSTRACT: In the title indole derivatives, C₂₂H₁₆N₂O₅S, (I) and C₂₀H₁₅NO₃S₂, (II), the sulfonyl-bound phenyl rings are almost orthogonal to the indole ring system, subtending dihedral angles of 88.33?(10) and 87.58?(16)°, respectively. In both compounds, the sulfonyl S atom has a distorted tetra-hedral geometry [O-S-O = 119.98?(9) and N-S-C = 104.01?(8)° for compound (I) and O-S-O = 120.08?(18) and N-S-C = 104.91?(14)° for compound (II)] and the sum of the bond angles at N indicates sp² hybridization. The mol-ecules of both (I) and (II) feature intra-molecular C-H?O hydrogen bonds that generate S(6) ring motifs with the sulfone O atom. In the crystals, mol-ecules of (I) are linked by C-H-O hydrogen bonds, forming R⁴₄(18) ring motifs while mol-ecules of (II) are linked by C-H-O and C-H-S hydrogen bonds, forming R²₂(12) ring motifs. Compound (II) was refined as an inversion twin.

SUBMITTER: Dhanalakshmi G 

PROVIDER: S-EPMC5730317 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature