Metronomic Chemotherapy in Triple-Negative Metastatic Breast Cancer: The Future Is Now?
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ABSTRACT:
SUBMITTER: Cazzaniga ME
PROVIDER: S-EPMC5733132 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Publications
Metronomic Chemotherapy in Triple-Negative Metastatic Breast Cancer: The Future Is Now?
Cazzaniga M E ME Cortesi L L Ferzi A A Scaltriti L L Cicchiello F F Ciccarese M M Torre S Della SD Villa F F Giordano M M Verusio C C Nicolini M M Gambaro A R AR Zanlorenzi L L Biraghi E E Casini E E Legramandi L L Rulli E E
International journal of breast cancer 20171203
Triple-negative breast cancer (TNBC) shows a very bad prognosis, even in early stages of disease. Metronomic chemotherapy refers to the minimum biologically effective dose of a chemotherapy agent given as a continuous dosing regimen with no prolonged drug-free breaks that leads to antitumor activity. In the present article, we review preclinical and clinical data of metronomic administration of chemotherapy agents with or without biological agents in TNBC cell lines and patients, contextually re ...[more]
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