Ontology highlight
ABSTRACT: Objective
To investigate the risk of dementia in patients with stroke who did and did not receive acupuncture treatment.Design
Retrospective cohort study.Setting
This study was based on Taiwan's National Health Insurance Research Database that included patients with stroke hospitalised between 1 January 2000 and 31 December 2004.Participants
We identified 11?220 patients aged 50 years and older with newly diagnosed stroke hospitalisation.Primary and secondary outcome measures
We compared the incident dementia during the follow-up period until the end of 2009 in patients with stroke who did and did not receive acupuncture. The adjusted HRs and 95% CIs of dementia associated with acupuncture were calculated in multivariate Cox proportional hazard regressions.Results
Acupuncture treatment was associated with a decreased risk of dementia with multivariate adjustment (HR, 0.73; 95%?CI 0.66 to 0.80), and the association was significant in both sexes and every age group, as well as in groups with ischaemic stroke, with fewer medical conditions and those hospitalised after stroke. Patients with stroke received acupuncture treatment, and conventional rehabilitation was associated with a significantly reduced risk of poststroke dementia (HR, 0.64; 95%?CI 0.56 to 0.74).Conclusions
This study raises the possibility that patients with non-haemorrhagic stroke who received acupuncture had a reduced risk of dementia. The results suggest the need for prospective sham-controlled and randomised trials to establish the efficacy of acupuncture in preventing dementia.
SUBMITTER: Shih CC
PROVIDER: S-EPMC5734214 | biostudies-literature | 2017 Jul
REPOSITORIES: biostudies-literature
Shih Chun-Chuan CC Yeh Chun-Chieh CC Hu Chaur-Jong CJ Lane Hsin-Long HL Tsai Chin-Chuan CC Chen Ta-Liang TL Liao Chien-Chang CC
BMJ open 20170705 6
<h4>Objective</h4>To investigate the risk of dementia in patients with stroke who did and did not receive acupuncture treatment.<h4>Design</h4>Retrospective cohort study.<h4>Setting</h4>This study was based on Taiwan's National Health Insurance Research Database that included patients with stroke hospitalised between 1 January 2000 and 31 December 2004.<h4>Participants</h4>We identified 11 220 patients aged 50 years and older with newly diagnosed stroke hospitalisation.<h4>Primary and secondary ...[more]