Ontology highlight
ABSTRACT:
SUBMITTER: Lin R
PROVIDER: S-EPMC5735190 | biostudies-literature | 2017 Dec
REPOSITORIES: biostudies-literature
Lin Rong R Ju Hongfang H Yuan Ziyu Z Zhang Caicai C Zeng Liangliang L Sun Yuantian Y Su Zhenyu Z Jin Li L
Scientific reports 20171218 1
Previous studies suggest that leptin (LEP) has an important role in glucose metabolism in the nonpregnant state. During pregnancy, circulating maternal concentrations of leptin rise significantly, mainly due to increased secretion of leptin from maternal adipose tissue and placenta. This study aimed to analyze the impact of maternal and fetal common LEP variants on glucose homeostasis in the pregnant state. Several glycemic traits, including fasting plasma glucose, fasting plasma insulin (FPI), ...[more]