Ontology highlight
ABSTRACT:
SUBMITTER: Li Y
PROVIDER: S-EPMC5738528 | biostudies-literature | 2017 Dec
REPOSITORIES: biostudies-literature
Li Yizeng Y He Lijuan L Gonzalez Nicolas A P NAP Graham Jenna J Wolgemuth Charles C Wirtz Denis D Sun Sean X SX
Biophysical journal 20171201 11
Cell shape changes during cytokinesis in eukaryotic cells have been attributed to contractile forces from the actomyosin ring and the actomyosin cortex. Here we propose an additional mechanism where active pumping of ions and water at the cell poles and the division furrow can also achieve the same type of shape change during cytokinesis without myosin contraction. We develop a general mathematical model to examine shape changes in a permeable object subject to boundary fluxes. We find that hydr ...[more]