Ontology highlight
ABSTRACT:
SUBMITTER: Martin WJ
PROVIDER: S-EPMC5742481 | biostudies-literature | 2017 Jan
REPOSITORIES: biostudies-literature
Martin William J WJ Reiter Nicholas J NJ
Biochemistry 20161229 1
Over billions of years of evolution, nature has embraced proteins as the major workhorse molecules of the cell. However, nearly every aspect of metabolism is dependent upon how structured RNAs interact with proteins, ligands, and other nucleic acids. Key processes, including telomere maintenance, RNA processing, and protein synthesis, require large RNAs that assemble into elaborate three-dimensional shapes. These RNAs can (i) act as flexible scaffolds for protein subunits, (ii) participate direc ...[more]