Ontology highlight
ABSTRACT:
SUBMITTER: Aoyama T
PROVIDER: S-EPMC5744175 | biostudies-literature | 2017 Dec
REPOSITORIES: biostudies-literature
CPT: pharmacometrics & systems pharmacology 20171123 12
We aimed to reanalyze the differences in the pharmacokinetics (PKs) of meloxicam in East Asian populations based on a population approach using previously published data and to investigate the factors found in population PK analysis that affect the pharmacodynamics (PDs) of meloxicam. Population PK analysis was performed in 119 healthy male subjects (30 Japanese, 30 Chinese, 29 Korean, and 30 white) under strictly controlled trial conditions with regulated meals and a single lot of the drug. We ...[more]