Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Aborigines of Taiwan and their genetic relationship to East Asian and Pacific populations

ABSTRACT: This SuperSeries is composed of the SubSeries listed below.

ORGANISM(S): Homo sapiens

PROVIDER: GSE152200 | GEO | 2020/06/10

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

The Ami and Yami aborigines of Taiwan and their genetic relationship to East Asian and Pacific populations

Project description:We combined new data with previously published data (PMID: 25877615, 26811443, 29379068, 18292342, 24297229, 27302840, 24395773 and 30846778) to compare phylogenetic relationships of the Ami and Yami aborigenes of Taiwan to groups from mainland Southeast Asia, island Southeast Asia and Oceania.

2021-08-23 | GSE152194 | GEO

The Ami and Yami aborigines of Taiwan and their genetic relationship to East Asian and Pacific populations.

Project description:This article reports on the genetic characteristics of the Ami and Yami, two aboriginal populations of Taiwan. Y-SNP and mtDNA markers as well as autosomal SNPs were utilized to investigate the phylogenetic relationships to groups from MSEA (mainland Southeast Asia), ISEA (island Southeast Asia), and Oceania. Both the Ami and Yami have limited genetic diversity, with the Yami having even less diversity than the Ami. The partitioning of populations within the PCA plots based on autosomal SNPs, the profile constitution observed in the structure analyses demonstrating similar composition among specific populations, the average IBD (identical by descent) tract length gradients, the average total length of genome share among the populations, and the outgroup f3 results all indicate genetic affinities among populations that trace a geographical arc from Taiwan south into the Philippine Archipelago, Borneo, Indonesia, and Melanesia. Conversely, a more distant kinship between the Ami/Yami and MSEA based on all the markers examined, the total mtDNA sequences as well as the admixture f3 and f4 analyses argue against strong genetic contribution from MSEA to the Austronesian dispersal. The sharing of long IBD tracts, total genome length, and the large number of segments in common between the Ami/Yami and the Society Archipelago populations East Polynesia standout considering they are located about 10,700 km apart.

| S-EPMC8298601 | biostudies-literature

Aborigines of Taiwan and their genetic relationship to East Asian and Pacific populations

Project description:Aborigines of Taiwan and their genetic relationship to East Asian and Pacific populations

| PRJNA638622 | ENA

The Ami and Yami aborigines of Taiwan and their genetic relationship to East Asian and Pacific populations

Project description:The Ami and Yami aborigines of Taiwan and their genetic relationship to East Asian and Pacific populations

| PRJNA638609 | ENA

Mitochondrial and nuclear genetic relationships among Pacific Island and Asian populations.

Project description:Mitochondrial and autosomal short tandem-repeat (STR) genetic distances among 28 Pacific Island and Asian populations are significantly correlated (r=.25, P<.01) but describe distinct patterns of relationships. Maternally inherited-mtDNA data suggest that Remote Oceanic Islanders originated in island Southeast Asia. In contrast, biparental STR data reveal substantial genetic affinities between Remote Oceanic Islanders and Near Oceanic populations from highland Papua New Guinea and Australia. The low correlation between maternal and biparental genetic markers from the same individuals may reflect differences in genome-effective population sizes or in sex-biased gene flow. To explore these possibilities, we have examined genetic diversity, gene flow, and correlations among genetic, linguistic, and geographic distances within four sets of populations representing potential geographic and cultural spheres of interaction. GST estimates (a measure of genetic differentiation inversely proportional to gene flow) from mtDNA sequences vary between 0.13 and 0.39 and are typically five times greater than GST estimates from STR loci (0.05-0.08). Significant correlations (r>.5, P<.05) between maternal genetic and linguistic distances are coincident with high mtDNA GST estimates (>0.38). Thus, genetic and linguistic distances may coevolve, and their correspondence may be preserved under conditions of genetic isolation. A significant correlation (r=.65, P<.01) between biparental genetic and geographic distances is coincident with a low STR GST estimate (0.05), indicating that isolation by distance is observed under conditions of high nuclear-gene flow. These results are consistent with an initial settlement of Remote Oceania from island Southeast Asia and with extensive postcolonization male-biased gene flow with Near Oceania.

| S-EPMC1377291 | biostudies-other

The Senescent Methylome and its relationship with cancer, ageing, and germline genetic variation in humans

Project description:This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

2015-07-24 | E-GEOD-58035 | biostudies-arrayexpress

The relationship between DNA methylation, genetic and expression inter-individual variation in untransformed human fibroblasts

Project description:This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

2013-12-13 | E-GEOD-53261 | biostudies-arrayexpress

Comparative genetic architectures of schizophrenia in East Asian and European populations.

Project description:Schizophrenia is a debilitating psychiatric disorder with approximately 1% lifetime risk globally. Large-scale schizophrenia genetic studies have reported primarily on European ancestry samples, potentially missing important biological insights. Here, we report the largest study to date of East Asian participants (22,778 schizophrenia cases and 35,362 controls), identifying 21 genome-wide-significant associations in 19 genetic loci. Common genetic variants that confer risk for schizophrenia have highly similar effects between East Asian and European ancestries (genetic correlation = 0.98 ± 0.03), indicating that the genetic basis of schizophrenia and its biology are broadly shared across populations. A fixed-effect meta-analysis including individuals from East Asian and European ancestries identified 208 significant associations in 176 genetic loci (53 novel). Trans-ancestry fine-mapping reduced the sets of candidate causal variants in 44 loci. Polygenic risk scores had reduced performance when transferred across ancestries, highlighting the importance of including sufficient samples of major ancestral groups to ensure their generalizability across populations.

| S-EPMC6885121 | biostudies-literature

Transcriptomic responses to high water temperature in Pacific salmon

Project description:This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

2013-11-01 | E-GEOD-42558 | biostudies-arrayexpress

Pacific salmon gill samples

Project description:This SuperSeries is composed of the SubSeries listed below.

2010-12-31 | GSE22179 | GEO