Ontology highlight
ABSTRACT:
SUBMITTER: Albert JM
PROVIDER: S-EPMC5745043 | biostudies-literature | 2016 May
REPOSITORIES: biostudies-literature
Albert Jeffrey M JM Geng Cuiyu C Nelson Suchitra S
Biometrical journal. Biometrische Zeitschrift 20150913 3
Health researchers are often interested in assessing the direct effect of a treatment or exposure on an outcome variable, as well as its indirect (or mediation) effect through an intermediate variable (or mediator). For an outcome following a nonlinear model, the mediation formula may be used to estimate causally interpretable mediation effects. This method, like others, assumes that the mediator is observed. However, as is common in structural equations modeling, we may wish to consider a laten ...[more]