Ontology highlight
ABSTRACT:
SUBMITTER: Culp-Hill R
PROVIDER: S-EPMC5745140 | biostudies-literature | 2017 Dec
REPOSITORIES: biostudies-literature
Culp-Hill Rachel R Zheng Connie C Reisz Julie A JA Smith Keith K Rachubinski Angela A Nemkov Travis T Butcher Eric E Granrath Ross R Hansen Kirk C KC Espinosa Joaquín M JM D'Alessandro Angelo A
Blood advances 20171221 27
Red blood cells (RBCs) are the most abundant cell in the human body. During their ∼120-day life span in the circulatory system, RBCs release oxygen to all human tissues while being exposed to tissue metabolic activity. Owing to the relative simplicity of their intrinsic metabolism and the abundance of metabolite transporters in RBC membranes, the metabolism of mature erythrocytes indirectly mirrors systemic metabolic homeostasis and its alterations as a function of physiological factors, such as ...[more]