SMORE: Synteny Modulator of Repetitive Elements.
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ABSTRACT:
SUBMITTER: Berkemer SJ
PROVIDER: S-EPMC5745555 | biostudies-literature | 2017 Oct
REPOSITORIES: biostudies-literature
Publications
SMORE: Synteny Modulator of Repetitive Elements.
Berkemer Sarah J SJ Hoffmann Anne A Murray Cameron R A CRA Stadler Peter F PF
Life (Basel, Switzerland) 20171031 4
Several families of multicopy genes, such as transfer ribonucleic acids (tRNAs) and ribosomal RNAs (rRNAs), are subject to concerted evolution, an effect that keeps sequences of paralogous genes effectively identical. Under these circumstances, it is impossible to distinguish orthologs from paralogs on the basis of sequence similarity alone. Synteny, the preservation of relative genomic locations, however, also remains informative for the disambiguation of evolutionary relationships in this situ ...[more]
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