Evaluation of laboratory tests for cirrhosis and for alcohol use, in the context of alcoholic cirrhosis.

ABSTRACT: Laboratory tests can play an important role in assessment of alcoholic patients, including for evaluation of liver damage and as markers of alcohol intake. Evidence on test performance should lead to better selection of appropriate tests and improved interpretation of results. We compared laboratory test results from 1578 patients between cases (with alcoholic cirrhosis; 753 men, 243 women) and controls (with equivalent lifetime alcohol intake but no liver disease; 439 men, 143 women). Comparisons were also made between 631 cases who had reportedly been abstinent from alcohol for over 60 days and 364 who had not. ROC curve analysis was used to estimate and compare tests' ability to distinguish patients with and without cirrhosis, and abstinent and drinking cases. The best tests for presenc

SUBMITTER: Whitfield JB 

PROVIDER: S-EPMC5745811 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature