Ontology highlight
ABSTRACT:
SUBMITTER: Li Y
PROVIDER: S-EPMC5746395 | biostudies-literature | 2017 Dec
REPOSITORIES: biostudies-literature
Li Yan Y Zhao Hongmei H Xu Qingyu Q Lv Na N Jing Yu Y Wang Lili L Wang Xiaowen X Guo Jing J Zhou Lei L Liu Jing J Chen Guofeng G Chen Chongjian C Li Yonghui Y Yu Li L
Oncotarget 20171130 66
Clinical and genetic features incompletely predict outcome in acute myeloid leukemia (AML). The value of clinical methylation assays for prognostic markers has not been extensively explored. We assess the prognostic implications of methylC-capture sequencing (MCC-Seq) in patients with de novo AML by integrating DNA methylation and genetic risk stratification. MCC-Seq assessed DNA methylation level in 44 samples. The differentially methylated regions associated with prognostic genetic information ...[more]