Ontology highlight
ABSTRACT:
SUBMITTER: Oyabu T
PROVIDER: S-EPMC5751356 | biostudies-literature | 2017 Dec
REPOSITORIES: biostudies-literature
Oyabu Takako T Myojo Toshihiko T Lee Byeong-Woo BW Okada Takami T Izumi Hiroto H Yoshiura Yukiko Y Tomonaga Taisuke T Li Yun-Shan YS Kawai Kazuaki K Shimada Manabu M Kubo Masaru M Yamamoto Kazuhiro K Kawaguchi Kenji K Sasaki Takeshi T Morimoto Yasuo Y
International journal of molecular sciences 20171219 12
The hazards of various types of nanoparticles with high functionality have not been fully assessed. We investigated the usefulness of biopersistence as a hazard indicator of nanoparticles by performing inhalation and intratracheal instillation studies and comparing the biopersistence of two nanoparticles with different toxicities: NiO and TiO₂ nanoparticles with high and low toxicity among nanoparticles, respectively. In the 4-week inhalation studies, the average exposure concentrations were 0.3 ...[more]