Ontology highlight
ABSTRACT:
SUBMITTER: Yao Q
PROVIDER: S-EPMC5752548 | biostudies-literature | 2017 Dec
REPOSITORIES: biostudies-literature
Yao Qian Q An Yu Y Hou Wei W Cao Ya-Nan YN Yao Meng-Fei MF Ma Ning-Ning NN Hou Lin L Zhang Hong H Liu Hai-Jing HJ Zhang Bo B
Oncotarget 20171130 65
Low density lipoprotein (LDL) receptor-related protein-6 (LRP6) is an important co-receptor of Wnt pathway, which plays a predominant role in development and progression of colorectal cancer. Recently, dysregulation of LRP6 has proved to be involved in the progression of cancers, but its biological role and clinical significance in colorectal cancer remain unclear. In present study, we revealed that phosphorylation of LRP6 was aberrantly upregulated in colorectal carcinoma correlating with TNM o ...[more]