Ontology highlight
ABSTRACT:
SUBMITTER: Subramanian S
PROVIDER: S-EPMC5754805 | biostudies-literature | 2017 Dec
REPOSITORIES: biostudies-literature
Proceedings of the National Academy of Sciences of the United States of America 20171201 51
Stator elements consisting of MotA<sub>4</sub>MotB<sub>2</sub> complexes are anchored to the cell wall, extend through the cell membrane, and interact with FliG in the cytoplasmic C ring rotor of the flagellum. The cytoplasmic loop of MotA undergoes proton-driven conformational changes that drive flagellar rotation. Functional regulators inhibit motility by either disengaging or jamming the stator-rotor interaction. Here we show that the YcgR homolog MotI (formerly DgrA) of <i>Bacillus subtilis< ...[more]