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ABSTRACT: Background
Relationships between birthweight and future obesity risk remain unclear.Objective
To assess associations between birthweight and later obesity in a nationally representative cohort of early school-aged children.Methods
We used linear and logistic regression to evaluate 10 186 term- or preterm children in the Early Childhood Longitudinal Study-Kindergarten Cohort 2011 for relationships between birthweight and later obesity and change in BMI z-score from kindergarten-to-second grade. All analyses were adjusted for sex, race/ethnicity, parental education and household income.Results
Compared to children born normal birthweight (NBW), high birthweight (HBW) term children and large-for-gestational-age (LGA) preterm children had significantly greater BMI z-scores from kindergarten-to-second grade (p < 0.001). Term children born HBW had higher odds of obesity by kindergarten (adjusted odds ratios [aOR] 1.91, p < 0.0001). Among preterm children, odds of obesity was higher among LGA children starting in first grade (aOR 2.34, p < 0.05) and among small-for-gestational age children in second grade (aOR 2.26, p < 0.05). Compared to NBW children, HBW children had greater change in BMI z-score between kindergarten-first grade (p < 0.01).Conclusions
High birthweight term and LGA preterm children had increased adjusted odds of obesity in school-age compared to their NBW counterparts. Physicians may provide counselling early in life for families of large infants to help prevent future obesity.
SUBMITTER: Kapral N
PROVIDER: S-EPMC5756526 | biostudies-literature | 2018 Jun
REPOSITORIES: biostudies-literature
Kapral N N Miller S E SE Scharf R J RJ Gurka M J MJ DeBoer M D MD
Pediatric obesity 20170706 6
<h4>Background</h4>Relationships between birthweight and future obesity risk remain unclear.<h4>Objective</h4>To assess associations between birthweight and later obesity in a nationally representative cohort of early school-aged children.<h4>Methods</h4>We used linear and logistic regression to evaluate 10 186 term- or preterm children in the Early Childhood Longitudinal Study-Kindergarten Cohort 2011 for relationships between birthweight and later obesity and change in BMI z-score from kinderg ...[more]