Ontology highlight
ABSTRACT:
SUBMITTER: Javvadi S
PROVIDER: S-EPMC5757255 | biostudies-literature | 2018 Jan
REPOSITORIES: biostudies-literature
Javvadi Sreegowrinadh S Pandey Sheo Shankar SS Mishra Amita A Pradhan Binod Bihari BB Chatterjee Subhadeep S
EMBO reports 20171208 1
Cellular iron homeostasis is critical for survival and growth. Bacteria employ a variety of strategies to sequester iron from the environment and to store intracellular iron surplus that can be utilized in iron-restricted conditions while also limiting the potential for the production of iron-induced reactive oxygen species (ROS). Here, we report that membrane-derived oligosaccharide (mdo) glucan, an intrinsic component of Gram-negative bacteria, sequesters the ferrous form of iron. Iron-binding ...[more]