Ontology highlight
ABSTRACT:
SUBMITTER: Bruce HA
PROVIDER: S-EPMC5758883 | biostudies-literature | 2018 Jan
REPOSITORIES: biostudies-literature
Bruce Heather A HA Du Dijun D Matak-Vinkovic Dijana D Bandyra Katarzyna J KJ Broadhurst R William RW Martin Esther E Sobott Frank F Shkumatov Alexander V AV Luisi Ben F BF
Nucleic acids research 20180101 1
The RNA degradosome is a multi-enzyme assembly that plays a central role in the RNA metabolism of Escherichia coli and numerous other bacterial species including pathogens. At the core of the assembly is the endoribonuclease RNase E, one of the largest E. coli proteins and also one that bears the greatest region predicted to be natively unstructured. This extensive unstructured region, situated in the C-terminal half of RNase E, is punctuated with conserved short linear motifs that recruit partn ...[more]