Investigation of quercetin and hyperoside as senolytics in adult human endothelial cells.
Ontology highlight
ABSTRACT: New and noteworthy
Previously, quercetin has been reported to be a senolytic, a drug that selectively removes senescent cells, in HUVECs. However, we found neither quercetin nor Q3G was effective as a senolytic for adult human endothelial cells.
SUBMITTER: Hwang HV
PROVIDER: S-EPMC5760026 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Publications
Investigation of quercetin and hyperoside as senolytics in adult human endothelial cells.
Hwang HyunTae V HV Tran Darlene Thuy DT Rebuffatti Michelle Nicole MN Li Chin-Shang CS Knowlton Anne A AA
PloS one 20180109 1
<h4>New and noteworthy</h4>Previously, quercetin has been reported to be a senolytic, a drug that selectively removes senescent cells, in HUVECs. However, we found neither quercetin nor Q3G was effective as a senolytic for adult human endothelial cells. ...[more]
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