Ontology highlight
ABSTRACT:
SUBMITTER: Vanden Heuvel JP
PROVIDER: S-EPMC5760202 | biostudies-literature | 2018 Jan
REPOSITORIES: biostudies-literature
Vanden Heuvel John P JP Maddox Ewa E Maalouf Samar W SW
eLife 20180109
In 2016, as part of the Reproducibility Project: Cancer Biology, we published a Registered Report (Vanden Heuvel et al., 2016), that described how we intended to replicate selected experiments from the paper 'Systematic identification of genomic markers of drug sensitivity in cancer cells' (Garnett et al., 2012). Here we report the results. We found Ewing's sarcoma cell lines, overall, were more sensitive to the PARP inhibitor olaparib than osteosarcoma cell lines; however, while the effect was ...[more]